Anti-PSMD6 Antibody Picoband® 0,00647 Vervoeging

26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene. This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants.

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

PSMD6

9861

Q15008

Human

No cross-reactivity with other proteins.

E.coli-derived human PSMD6 recombinant protein (Position: E30-Q381) .

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Flow Cytometry

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Immunogen affinity purified.

Liquid

Plays a role in B-cell proliferation and differentiation.

1. Li, J., Cao, Y., Xu, X., Xiang, H., Zhang, Z., Chen, B., Hao, Y., Wei, Z., Zhou, P., Chen, D. Increased new lncRNA-mRNA gene pair levels in human cumulus cells correlate with oocyte maturation and embryo development. Reprod. Sci. 22: 1008-1014, 2015. 2. Nagase, T, Miyajima, N, Tanaka, A., Sazuka, T., Seki, N., Sato, S., Tabata, S., Ishikawa, K., Kawarabayashi, Y., Kotani, H., Nomura, N. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2: 37-43, 1995. 3. Ren, S., Smith, M. J., Louro, I. D., McKie-Bell, P., Bani, M. R., Wagner, M., Zochodne, B., Redden, D. T., Grizzle, W. E., Wang, N., Smith, D. I., Herbst, R. A., Bardenheuer, W., Opalka, B., Schutte, J., Trent, J. M., Ben-David, Y., Ruppert, J. M. The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma. Oncogene 19: 1419-1427, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

CD72 molecule

Membrane; Single-pass type II membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.