Anti-PTCD3 Antibody Picoband® Biotin Conjugated

Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol; mitochondrial matrix; and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.

PTCD3; MRPS39; TRG15; Pentatricopeptide repeat domain-containing protein 3, mitochondrial; 28S ribosomal protein S39, mitochondrial; MRP-S39; Mitochondrial small ribosomal subunit protein mS39; Transformation-related gene 15 protein; TRG-15

PTCD3

55037

Q96EY7

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human PTCD3 recombinant protein (Position: D66-R648) . Human PTCD3 shares 76.4% amino acid (aa) sequence identity with mouse PTCD3.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

79 kDa

Pentatricopeptide repeat domain 3

Small ribosomal subunit protein mS39

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.