Anti-PTER Antibody Picoband® 31.0550 Vervoeging

PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.

Epidermal growth factor-like protein 6; EGF-like protein 6; MAM and EGF domains-containing gene protein; EGFL6; MAEG; PP648; UNQ281/PRO320

PTER

9317

Q96BW5

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PTER recombinant protein (Position: M1-H315) .

Ubiquitous.

Flow Cytometry

Growth Factors/Hormones, Signal Transduction

Immunogen affinity purified.

Liquid

May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity) .

1. Alimova-Kost, M. V., Imreh, S., Buchman, V. L., Ninkina, N. N. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet. Cell Genet. 83: 16-17, 1998. 2. Davies, J. A., Buchman, V. L., Krylova, O., Ninkina, N. N. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett. 410: 378-382, 1997. 3. Hou, X., Maser, R. L., Magenheimer, B. S., Calvet, J. P. A mouse kidney- and liver-expressed cDNA having homology with a prokaryotic parathion hydrolase (phosphotriesterase) -encoding gene: abnormal expression in injured and polycystic kidneys. Gene 168: 157-163, 1996.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

EGF like domain multiple 6

Basement membrane.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.