Anti-PTGR2 Antibody Picoband® 31.0550 Vervoeging

This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

PTGR2

145482

Q8N8N7

Human

No cross-reactivity with other proteins

E.coli-derived human PTGR2 recombinant protein (Position: E26-Q305) .

Ubiquitous. Highly expressed in brain. .

Flow Cytometry

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

1. Yun-Chia, C. E. , Yi-Cheng, C. , Chia-Tung, S. , Yu-Wen, T. , Shu-Huei, T. , & Siow-Wey, H. , et al. (2016) . Inhibition of prostaglandin reductase 2, a putative oncogene overexpressed in human pancreatic adenocarcinoma, induces oxidative stress-mediated cell death involving xct and cth gene expressions through 15-keto-pge2. Plos One, 11 (1), e0147390. 2. Yun-Chia Chang, E. , Tsai, S. H. , Shun, C. T. , Hee, S. W. , Chang, Y. C. , & Tsai, Y. C. , et al. (2012) . Prostaglandin reductase 2 modulates ros-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients. American Journal of Pathology, 181 (4), 1316-1326. 3. Gao, K. , Lockwood, W. , Li, J. , Lam, W. , & Li, G. . (2008) . Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells. International Journal of Oncology, 32 (6), 1343-1349.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Protein NDRG3

Membrane ; Single-pass type I membrane protein .

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.