Anti-pyruvaatdehydrogenase E1 bèta subeenheid PDHB Monoklonale Antilichaam

Boster Bio Anti-Pyruvate Dehydrogenase E1 beta subunit PDHB Monoclonal Antibody catalog # M03998. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5;2.7.12.2; MAPK/ERK kinase 5; MEK 5; MAP2K5; MEK5, MKK5, PRKMK5

PDHB

5162

P11177

Human, Mouse, Rat

A synthesized peptide derived from human Pyruvate Dehydrogenase E1 beta subunit The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2) . It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) .

Clone: AEAD-16

Expressed in many adult tissues. Abundant in heart and skeletal muscle.

WB, IHC, ICC, IF, IP, Flow Cytometry

Cancer, Cardiogenesis, Cardiovascular, MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Serine/Threonine Kinases, Signal Transduction, Transcription Factors/Regulators

Affinity-chromatography

0.5mg/ml

Liquid

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M03998

35 kDa

35 kDa

Dual specificity mitogen-activated protein kinase kinase 5

Cytoplasm, cytoskeleton . Cell projection, lamellipodium . At the interface between the lamellipodial actin meshwork and the membrane. .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.