Anti-QRSL1 Antibody Picoband®

Contributes to glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA (Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 40.

Boster Bio Anti-QRSL1 Antibody Picoband® catalog # A13528-2. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

QRSL1; Glutamyl-tRNA (Gln amidotransferase subunit A, mitochondrial; Glu-AdT subunit A; EC 6.3.5.7; Glutaminyl-tRNA synthase-like protein 1

QRSL1

55278

Q9H0R6

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human QRSL1 recombinant protein (Position: M1-Q528) . Human QRSL1 shares 88.1% and 87% amino acid (aa) sequence identity with mouse and rat QRSL1, respectively.

WB, IHC, Flow Cytometry, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Friederich, M. W., Timal, S., Powell, C. A., Dallabona, C., Kurolap, A., Palacios-Zambrano, S., Bratkovic, D., Derks, T. G. J., Bick, D., Bouman, K., Chatfield, K. C., Damouny-Naoum, N., and 41 others. Pathogenic variants in glutamyl-tRNA (Gln) amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nature Commun. 9: 4065, 2018. Note: Electronic Article. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/16/2016. 3. Kamps, R., Szklarczyk, R., Theunissen, T. E., Hellebrekers, D. M. E. I., Sallevelt, S. C. E. H., Boesten, I. B., de Koning, B., van den Bosch, B. J., Salomons, G. S., Simas-Mendes, M., Verdijk, R., Schoonderwoerd, K., de Coo, I. F. M., Vanoevelen, J. M., Smeets, H. J. M. Genetic defects in mtDNA-encoded protein translation cause pediatric, mitochondrial cardiomyopathy with early-onset brain disease. Europ. J. Hum. Genet. 26: 537-551, 2018.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A13528-2

57 kDa

57 kDa

6

Glutaminyl-tRNA amidotransferase subunit QRSL1

Glutamyl-tRNA (Gln) amidotransferase subunit A, mitochondrial

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.