Anti-Quescin Q6/QSOX1 Antibody Picoband®

Sulfhydryl oxidase 1 is an enzyme that in humans is encoded by the QSOX1 gene. This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

Boster Bio Anti-Quiescin Q6/QSOX1 Antibody Picoband® catalog # A04549-1. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1; Xcl1; Lptn; Ltn; Scyc1

QSOX1

5768

O00391

Human

No cross-reactivity with other proteins.

E.coli-derived human Quiescin Q6/QSOX1 recombinant protein (Position: R32-Q421) .

Expressed in activated CD8 (+) T cells. In the thymus, expressed by medullary thymic epithelial cells.

WB, ELISA

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.

1. Alon, A., Grossman, I., Gat, Y., Kodali, V. K., DiMaio, F., Mehlman, T., Haran, G., Baker, D., Thorpe, C., Fass, D. The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature 488: 414-418, 2012. 2. Coppock, D. L., Cina-Poppe, D., Gilleran, S. The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. Genomics 54: 460-468, 1998. 3. Coppock, D. L., Kopman, C., Scandalis, S., Gilleran, S. Preferential gene expression in quiescent human lung fibroblasts. Cell Growth Differ. 4: 483-493, 1993.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A04549-1

105 kDa

Chemokine (C motif) ligand 1

Secreted.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.