Anti-R Cbwd1 Antilichaam (C-term)

Boster Bio Anti-R Cbwd1 Antibody (C-term) (Catalog # A15555) . Tested in WB application (s) . This antibody reacts with Rat.

COBW domain-containing protein 1, Cobalamin synthase W domain-containing protein 1, Cbwd1

ZNG1

Q99MB4

Rat

This Rat Cbwd1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-351 amino acids from the C-terminal region of rat Cbwd1.

WB

Cell Biology, Neuroscience

This antibody is purified through a protein A column, followed by peptide affinity purification.

Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1 to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1.

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A15555

43931 Da

WB: 1:1000

Nucleus {ECO:0000250|UniProtKB:Q8VEH6}.

Rabbit IgG

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.