Anti-Rab-3A-interactief eiwit RAB3IP Antilichaam

Boster Bio Anti-Rab-3A-interacting protein RAB3IP Antibody catalog # A09085. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Rab-3A-interacting protein; Rab3A-interacting protein; Rabin-3; SSX2-interacting protein; RAB3IP ; RABIN8

RAB3IP

Q96QF0

Human, Mouse, Rat

The antiserum was produced against synthesized peptide derived from human RAB3IP. AA range:257-306

Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver. .

WB, IHC, IF, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09085

53021 MW

Rab-3A-interacting protein

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin.

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.