Anti-RAB43 Antibody Picoband® 31.0647 Vervoeging

Ras-related GTP-binding protein 43 (RAB43) is a member ofthe Rassuperfamily. RAB43 is mainly located in endoplasmic reticulum and Golgi, and plays a role as a key regulator of vesicle movement, signal transduction and tethering membrane eventsin membrane trafficking.

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

RAB43

339122

Q86YS6

Human

No cross-reactivity with other proteins.

E.coli-derived human RAB43 recombinant protein (Position: Q14-E206) .

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Flow Cytometry

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Immunogen affinity purified.

Liquid

Plays a role in B-cell proliferation and differentiation.

1. Jiang, Y. , Sun, Y. , Hu, J. , Yu, N. , & Xu, H. . (2019) . A germline mutation in rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome. BMC Cancer, 19 (1) . 2. ChunmanLi, ZheWei, YiFan, WeiHuang, YunchaoSu, & HonglinLi, et al. (2017) . The gtpase rab43 controls the anterograde er-golgi trafficking and sorting of gpcrs. Cell Reports. 3. Ming-Zhi, Han, Bin, Huang, An-Jing, & Chen, et al. (2017) . High expression of rab43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. Oncology reports.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

CD72 molecule

Membrane; Single-pass type II membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.