Anti-RAP80 Monoklonale antilichamen

Boster Bio Anti-RAP80 Monoclonal Antibody catalog # M06262. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Tumor necrosis factor receptor superfamily member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FGF-inducible 14; Tweak-receptor; TweakR; CD266; TNFRSF12A; FN14

UIMC1

51720

Q96RL1

Human

A synthesized peptide derived from human RAP80 Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

Clone: ADCH-21

Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

WB, IHC, ICC, IF

DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Nuclear Receptors, Nuclear Signaling Pathways, Ubiquitin & Ubiquitin Like Modifiers

Affinity-chromatography

0.5mg/ml

Liquid

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M06262

13911 MW

70,90 kDa

Tumor necrosis factor receptor superfamily member 12A

Membrane; Single-pass type I membrane protein.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.