Anti-Ras-gerelateerd eiwit Rab-43 RAB43 Antilichaam

Boster Bio Anti-Ras-related protein Rab-43 RAB43 Antibody catalog # A09315. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Ras-related protein Rab-43; Ras-related protein Rab-41; RAB43; RAB41

RAB43

Q86YS6

Human, Mouse, Rat

Synthesized peptide derived from human protein at AA range: 90-170

Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver.

WB, ELISA

RAB43 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/mL

Liquid

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09315

23339 MW

Ras-related protein Rab-43

Cytoplasmic vesicle, phagosome

Ras-related protein Rab-43

IgG

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.