Anti-RASL12 Antibody Picoband® 0,00647 Vervoeging

Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.

RASL12

51285

Q9NYN1

Human

E.coli-derived human RASL12 recombinant protein (Position: K7-K261) . Human RASL12 shares 93.3% amino acid (aa) sequence identity with mouse RASL12.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Wistow, G., Bernstein, S. L., Ray, S., Wyatt, M. K., Behal, A., Touchman, J. W., ... & Peterson, K. (2002) . Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. Mol Vis, 8 (21), 185-195. 2. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., ... & Wrana, J. L. (2005) . High-throughput mapping of a dynamic signaling network in mammalian cells. Science, 307 (5715), 1621-1625. 3. Lipp, J. J., Marvin, M. C., Shokat, K. M., & Guthrie, C. (2015) . SR protein kinases promote splicing of nonconsensus introns. Nature structural & molecular biology, 22 (8), 611.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

30,29,27 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.