Anti-RBP2 Antilichaam Picoband® fluoro550 Vervoeging

RBP2 (Retinol-binding protein 2) is a protein that in humans is encoded by the RBP2 gene. RBP2 is an abundant protein present in the small intestinal epithelium. It is though to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. RBP2 may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle.

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1; ATP-dependent helicase 1; hHEL1; SMARCAD1; KIAA1122

RBP2

5948

P50120

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human RBP2 recombinant protein (Position: E10-K99) .

Isoform 1 is expressed ubiquitously. Isoform 3 is expressed mainly in skin, fibroblasts, keratinocytes and esophagus.

Flow Cytometry

Chromatin Remodeling, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by ing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing.

1. Demmer, L. A., Birkenmeier, E. H., Sweetser, D. A., Levin, M. S., Zollman, S., Sparkes, R. S., Mohandas, T., Lusis, A. J., Gordon, J. I. The cellular retinol binding protein II gene: sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene.J. Biol. Chem. 262: 2458-2467, 1987.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

80420 MW

6

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

Nucleus. Chromosome.

Long-chain-fatty-acid--CoA ligase 3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.