Anti-REM2 Antibody Picoband® PE Vervoeging

Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity. Predicted to be active in plasma membrane.

REM2; GTP-binding protein REM 2; Rad and Gem-like GTP-binding protein 2

REM2

161253

Q8IYK8

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human REM2 recombinant protein (Position: R65-E257) . Human REM2 shares 94.8% and 95.9% amino acid (aa) sequence identity with mouse and rat REM2, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Bierings, R., Beato, M., Edel, M. J. An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19 (ARF) expression that promotes endothelial cell proliferation and angiogenesis. J. Biol. Chem. 283: 4408-4416, 2008. 2. Edel, M. J., Menchon, C., Menendez, S., Consiglio, A., Raya, A., Belmonte, J. C. I. Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev. 24: 561-573, 2010. 3. Finlin, B. S., Shao, H., Kadono-Okuda, K., Guo, N., Andres, D. A. Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases. Biochem. J. 347: 223-231, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

37 kDa

6

RRAD and GEM like GTPase 2

GTP-binding protein REM 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.