Anti-REPS2 Antibody Picoband® FITC-vervoeging

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

REPS2; POB1; RalBP1-associated Eps domain-containing protein 2; Partner of RalBP1; RalBP1-interacting protein 2

REPS2

9185

Q8NFH8

Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human REPS2 recombinant protein (Position: A76-K564) . Human REPS2 shares 88.4% amino acid (aa) sequence identity with mouse REPS2.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Feig, L. A. Ral-GTPases: approaching their 15 minutes of fame. Trends. Cell Biol. 13: 419-425, 2003. 2. Ikeda, M., Ishida, O., Hinoi, T., Kishida, S., Kikuchi, A. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J. Biol. Chem. 273: 814-821, 1998. 3. Kariya, K., Koyama, S., Nakashima, S., Oshiro, T., Morinaka, K., Kikuchi, A. Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation. J. Biol. Chem. 275: 18399-18406, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

72 kDa

6

RALBP1 associated Eps domain containing 2

RalBP1-associated Eps domain-containing protein 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.