Anti-RGS9 Antibody Picoband®

Regulator of G-protein signaling 9, also known as RGS9 is a human gene, which codes for a protein involved in regulation of signal transduction inside cells. This gene is mapped to 17q24.1. This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.

Boster Bio Anti-RGS9 Antibody Picoband® catalog # A04748-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; G-protein coupled receptor 2; CCR10; GPR2

RGS9

8787

O75916

Human

No cross-reactivity with other proteins.

E.coli-derived human RGS9 recombinant protein (Position: R13-D638) .

Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.

WB, ICC, IF, Flow Cytometry, ELISA

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.

1. Cabrera-Vera, T. M., Hernandez, S., Earls, L. R., Medkova, M., Sundgren-Andersson, A. K., Surmeier, D. J., Hamm, H. E. RGS9-2 modulates D2 dopamine receptor-mediated Ca (2+) channel inhibition in rat striatal cholinergic interneurons. Proc. Nat. Acad. Sci. 101: 16339-16344, 2004. 2. Hu, G., Zhang, Z., Wensel, T. G. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. J. Biol. Chem. 278: 14550-14554, 2003. 3. Sierra, D. A., Gilbert, D. J., Householder, D., Grishin, N. V., Yu, K., Ukidwe, P., Barker, S. A., He, W., Wensel, T. G., Otero, G., Brown, G., Copeland, N. G., Jenkins, N. A., Wilkie, T. M. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79: 177-185, 2002.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A04748-1

77 kDa

6

C-C motif chemokine receptor 10

Cell membrane, Multi-pass membrane protein.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.