Anti-RIM2 RIMS2 Antilichaam

Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.

Boster Bio Anti-RIM2 RIMS2 Antibody (Catalog # A09915) . Tested in ELISA, IHC-P applications. This antibody reacts with Human.

OBOE, RIM2, RAB3IP3, KIAA0751, Regulating synaptic membrane exocytosis protein 2, Rab-3-interacting molecule 2, RIM 2

RIMS2

Q9UQ26

Human

RIM2 antibody was raised against a 16 amino acid peptide near the carboxy terminusof human RIM2. The immunogen is located within amino acids 30 - 80 of RIM2.

Expressed in melanocytes (PubMed:23999003) .

ELISA, IHC-P

Neuroscience

RIM2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

https://www.bosterbio.com/msds?sku=A09915

160403 MW

Regulating synaptic membrane exocytosis 2

Cell membrane ; Peripheral membrane protein . Cell junction, synapse . Cell junction, synapse, presynaptic cell membrane ; Peripheral membrane protein .

Rat, Mouse

Regulating synaptic membrane exocytosis 2

IgG

RIM2 Antibody is supplied in PBS containing 0.02% sodium azide.