Anti-RIOK1 Antilichaam

Boster Bio Anti-RIOK1 Antibody catalog # A10785. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Serine/threonine-protein kinase RIO1;2.7.11.1

RIOK1

Q9BRS2

Human, Mouse, Rat

Synthesized peptide derived from the Internal region of human RIOK1.

IHC, IF, ELISA

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/mL

Liquid

Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre- rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (PubMed:22072790) . The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity) . Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity) . The catalytic activity regulates its dynamic association with the 40S subunit (By similarity) . In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation (PubMed:21081503) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10785

65583 MW

Serine/threonine-protein kinase RIO1

Cytoplasm, cytosol

Serine/threonine-protein kinase RIO1

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.