Anti-RNA helicase Mov10l1 MOV10L1 Antilichaam

Boster Bio Anti-RNA helicase Mov10l1 MOV10L1 Antibody catalog # A09677. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

RNA helicase Mov10l1 ;3.6.4.13 ; Moloney leukemia virus 10-like protein 1 ; MOV10-like protein 1 ; MOV10L1

MOV10L1

Q9BXT6

Human, Mouse

The antiserum was produced against synthesized peptide derived from human MOV10L1. AA range:318-367

Isoform 1: Specifically expressed in testis. .

WB, IHC, IF, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09677

135293 MW

RNA helicase Mov10l1

Cytoplasm . Component of the meiotic nuage, also named P granule, a germ- cell-specific organelle required to repress transposon activity during meiosis. .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.