Anti-RNF220 Antibody Picoband® 31.0647 Vervoeging

Enables beta-catenin binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within positive regulation of DNA-binding transcription factor activity and protein monoubiquitination. Located in nuclear lamina. Part of protein-containing complex. Implicated in hypomyelinating leukodystrophy 23.

RNF220; C1orf164; E3 ubiquitin-protein ligase RNF220; EC 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220

RNF220

55182

Q5VTB9

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human RNF220 recombinant protein (Position: M1-L566) . Human RNF220 shares 97.9% amino acid (aa) sequence identity with mouse RNF220.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/12/2014. 2. Kong, Q., Zeng, W., Wu, J., Hu, W., Li, C., Mao, B. RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination. Biochem. Biophys. Res. Commun. 393: 708-713, 2010. 3. Leuzzi, V., Rinna, A., Gallucci, M., Di Capua, M., Dionisi-Vici, C., Longo, D., Bertini, E. Ataxia, deafness, leukodystrophy: inherited disorder of the white matter in three related patients. Neurology 54: 2325-2328, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

63 kDa

6

Ring finger protein 220

E3 ubiquitin-protein ligase RNF220

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.