Anti-RPA Interactieve Proteïne Antilichaam

Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

Boster Bio Anti-RPA Interacting Protein Antibody (Catalog # A11439) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

RIP, HRIP, RIP, RPA-interacting protein, hRIP

RPAIN

Q86UA6

Human, Mouse, Rat

RPA IP antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RPA IP. The immunogen is located within the last 50 amino acids of RPA Interacting Protein.

Widely expressed. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain, heart, leukocytes, colon, intestine, ovary, testis, prostate, thymus and spleen.

ELISA, WB, IHC-P

Homeostasis

RPA Interacting Protein Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.

RPA Interacting Protein antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A11439

24770 MW

RPA interacting protein

Isoform 1: Cytoplasm. Nucleus.

RPA interacting protein

IgG

RPA Interacting Protein Antibody is supplied in PBS containing 0.02% sodium azide.