Anti-RPH3A Antibody Picoband® fluoro488 Vervoeging

Rabphilin-3A is a protein that in humans is encoded by the RPH3A gene. The protein encoded by this gene is thought to be an effector for RAB3A, which is a small G protein that acts in the late stages of neurotransmitter exocytosis. The encoded protein may be involved in neurotransmitter release and synaptic vesicle traffic.

Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

RPH3A

22895

Q9Y2J0

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human RPH3A recombinant protein (Position: R78-Q564) .

Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Flow Cytometry

Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

Immunogen affinity purified.

Liquid

The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

1. Inagaki, N., Mizuta, M., Seino, S. Cloning of a mouse rabphilin-3A expressed in hormone-secreting cells. J. Biochem. 116: 239-242, 1994. 2. Lin, C.-C., Huang, C.-C., Lin, K.-H., Cheng, K.-H., Yang, D.-M., Tsai, Y.-S., Ong, R.-Y., Huang, Y.-N., Kao, L.-S. Visualization of Rab3A dissociation during exocytosis: a study by total internal reflection microscopy. J. Cell. Physiol. 211: 316-326, 2007. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 63-70, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Pre T cell antigen receptor alpha

Membrane; Single-pass type I membrane protein.

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.