Anti-RPL23 Antibody Picoband® 31.0550 Vervoeging

60S ribosomal protein L23 is a protein that in humans is encoded by the RPL23 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

S-adenosylmethionine decarboxylase proenzyme; AdoMetDC; SAMDC; 4.1.1.50

RPL23

9349

P62829

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human RPL23 recombinant protein (Position: A12-A136) .

Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.

Flow Cytometry

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Immunogen affinity purified.

Liquid

Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

1. Berchtold, M. W., Berger, M. C. Isolation and analysis of a human cDNA highly homologous to the yeast gene encoding L17A ribosomal protein. Gene 102: 283-288, 1991. 2. Dai, M.-S., Shi, D., Jin, Y., Sun, X.-X., Zhang, Y., Grossman, S. R., Lu, H. Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism. J. Biol. Chem. 281: 24304-24313, 2006. 3. Herault, Y., Michel, D., Chatelain, G., Brun, G. cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17. Nucleic Acids Res. 19: 4001 only, 1991.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Adenosylmethionine decarboxylase 1

Nucleus.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.