Anti-RPRD1B Antibody Picoband® 31.0647 Vervoeging

Enables RNA polymerase II complex binding activity and identical protein binding activity. Involved in positive regulation of cell population proliferation; regulation of cell cycle process; and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of RNA polymerase II, holoenzyme.

Fascin-2; Retinal fascin; FSCN2

RPRD1B

58490

Q9NQG5

Human, Monkey

No cross-reactivity with other proteins.

E.coli-derived human RPRD1B recombinant protein (Position: R79-K272) .

Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.

Flow Cytometry

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Liquid

Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 6/22/2012. 2. Lu, D., Wu, Y., Wang, Y., Ren, F., Wang, D., Su, F., Zhang, Y., Yang, X., Jin, G., Hao, X., He, D., Zhai, Y., Irwin, D. M., Hu, J., Sung, J. J. Y., Yu, J., Jia, B., Chang, Z. CREPT accelerates tumorigenesis by regulating the transcription of cell-cycle-related genes. Cancer Cell 21: 92-104, 2012. 3. Ni, Z., Olsen, J. B., Guo, X., Zhong, G., Ruan, E. D., Marcon, E., Young, P., Guo, H., Li, J., Moffat, J., Emili, A., Greenblatt, J. F. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. Transcription 2: 237-242, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

49229 MW

6

Fascin actin-bundling protein 2, retinal

Nucleus.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.