Anti-RPS14 Antibody Picoband® 0,00647 Vervoeging

40S ribosomal protein S14 is a protein that in humans is encoded by the RPS14 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

P-selectin glycoprotein ligand; Selplg; Psgl1

RPS14

6208

P62263

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human RPS14 recombinant protein (Position: M1-L151) .

Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.

Flow Cytometry

Cardiovascular, Cell Biology, Platelets, Protease Inhibitors, Proteolysis/Ubiquitin, Proteolytic Enzymes

Immunogen affinity purified.

Liquid

A SLe (x) -type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.

1. Chen, I.-T., Dixit, A., Rhoads, D. D., Roufa, D. J. Homologous ribosomal proteins in bacteria, yeast, and humans. Proc. Nat. Acad. Sci. 83: 6907-6911, 1986. 2. Dana, S., Wasmuth, J. J. Linkage of the leuS, emtB, and chr genes on chromosome 5 in humans and expression of human genes encoding protein synthetic components in human-Chinese hamster hybrids. Somat. Cell Genet. 8: 245-264, 1982. 3. Dana, S., Wasmuth, J. J. Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5. Molec. Cell. Biol. 2: 1220-1228, 1982.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

28461 MW

6

Selectin P ligand

Integral component of membrane.

Breast cancer metastasis-suppressor 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.