Anti-RTL1 Antibody Picoband® 0,00647 Vervoeging

RTL1 (retrotransposon like 1) is a retrotransposon derived protein coding gene. This gene is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. This gene is essential for maintenance of the fetal capillaries.

RTL1

388015

A6NKG5

Human, Mouse, Rat

E.coli-derived human RTL1 recombinant protein (Position: H446-R1327) . Human RTL1 shares 68.3% amino acid (aa) sequence identity with mouse RTL1.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Davis, E., Caiment, F., Tordoir, X., Cavailli, J., Ferguson-Smith, A., Cockett, N., Georges, M., Charlier, C. RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus. Curr. Biol. 15: 743-749, 2005. Note: Erratum: Curr. Biol. 15: 884 only, 2005. 2. Kagami, M., Sekita, Y., Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y., Matsuoka, K., Takahashi, T., and 12 others. Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd (14) -like phenotypes. Nature Genet. 40: 237-242, 2008. 3. Seitz, H., Youngson, N., Lin, S.-P., Dalbert, S., Paulsen, M., Bachellerie, J.-P., Ferguson-Smith, A. C., Cavaille, J. Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nature Genet. 34: 261-262, 2003.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

155 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.