Anti-RTL3 Antibody Picoband® 31.0550 Vervoeging

Retrotransposon Gag like 3 is a protein that in humans is encoded by the RTL3 gene. This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell.

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

RTL3

203430

Q8N8U3

Human

No cross-reactivity with other proteins.

E.coli-derived human RTL3 recombinant protein (Position: Q168-Q475) .

Ubiquitously expressed.

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

1. Jürgen Brandt, Schrauth, S. , Veith, A. M. , Froschauer, A. , Haneke, T. , & Schultheis, C. , et al. (2005) . Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene, 345 (1), 101-111. 2. Brandt, J. , Veith, A. M. , & Volff, J. N. . (2005) . A family of neofunctionalized ty3/gypsy retrotransposon genes in mammalian genomes. Cytogenetic & Genome Research, 110 (1-4), 307-317. 3. Ota, T. , Suzuki, Y. , Nishikawa, T. , Otsuki, T. , & Sugano, S. . (2004) . Complete sequencing and characterization of 21,243 full-length human cdnas. Nature Genetics, 36 (1), 40-45.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14377 MW

6

Retrotransposon Gag like 10

Cell membrane; Lipid-anchor, GPI-anchor.

Lymphocyte antigen 6A-2/6E-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.