Anti-RUFY1 Antibody Picoband® fluoro488 Vervoeging

RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene. This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

RUFY1

80230

Q96T51

Human

No cross-reactivity with other proteins

E.coli-derived human RUFY1 recombinant protein (Position: L20-Q650) .

Ubiquitous. Highly expressed in brain. .

Flow Cytometry

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

1. Yang, J., Kim, O., Wu, J., Qiu, Y. Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1: a possible role of ETK in regulation of vesicle trafficking. J. Biol. Chem. 277: 30219-30226, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Protein NDRG3

Membrane ; Single-pass type I membrane protein .

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.