Anti-SAMHD1 Monoklonale antilichamen

Boster Bio Anti-SAMHD1 Monoclonal Antibody catalog # M00592. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71; Transferrin receptor protein 1, serum form; sTfR; TFRC

SAMHD1

25939

Q9Y3Z3

Human

A synthesized peptide derived from human SAMHD1

Clone: AEEA-19

Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells; isoform beta-3C is specifically expressed in prostate and testis.

WB, IHC, ICC, IF, Flow Cytometry

Host-Virus Interaction, Interspecies Interaction, Microbiology

Affinity-chromatography

0.5mg/ml

Liquid

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity) . A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00592

84871 MW

32-42 kDa, 65 kDa, 75 kDa

Transferrin receptor protein 1

Cell membrane ; Single-pass type II membrane protein . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.