Anti-SARDH Antibody Picoband®

Sarcosine dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the SARDH gene. This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described.

Boster Bio Anti-SARDH Antibody Picoband® catalog # A09641-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Band 4.1-like protein 5; EPB41L5; KIAA1548

SARDH

1757

Q9UL12

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SARDH recombinant protein (Position: M1-E640) .

Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

WB, Flow Cytometry, ELISA

Epigenetics and Nuclear Signaling, Mediator Complex, Transcription

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells.

1. Bar-joseph, I., Pras, E., Reznik-Wolf, H., Marek-Yagel, D., Abu-Horvitz, A., Dushnitzky, M., Goldstein, N., Rienstein, S., Dekel, M., Pode-Shakked, B., Zlotnik, J., Benarrosh, A., Gillery, P., Hofliger, N., Auray-Blais, C., Garnotel, R., Anikster, Y. Mutations in the sarcosine dehydrogenase gene in patients with sarcosinemia. Hum. Genet. 131: 1805-1810, 2012. 2. Brunialti, A. L. B., Harding, C. O., Wolff, J. A., Guenet, J.-L. The mouse mutation sarcosinemia (sar) maps to chromosome 2 in a region homologous to human 9q33-q34. Genomics 36: 182-184, 1996. 3. Eschenbrenner, M., Jorns, M. S. Cloning and mapping of the cDNA for human sarcosine dehydrogenase, a flavoenzyme defective in patients with sarcosinemia. Genomics 59: 300-308, 1999.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A09641-1

101 kDa

6

Erythrocyte membrane protein band 4.1 like 5

Cell membrane. Single-pass membrane protein. Postsynaptic cell membrane.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.