Anti-SCAI Antibody Picoband® Biotin Conjugated

This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A) -Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described.

SCAI; C9orf126; Protein SCAI; Suppressor of cancer cell invasion protein

SCAI

286205

Q8N9R8

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human SCAI recombinant protein (Position: M1-A549) . Human SCAI shares 98.2% amino acid (aa) sequence identity with mouse SCAI.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Brandt, D. T., Baarlink, C., Kitzing, T. M., Kremmer, E., Ivaska, J., Nollau, P., Grosse, R. SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta-1-integrin. Nature Cell Biol. 11: 557-567, 2009. 2. Fintha, A., Gasparics, A., Fang, L., Erdei, Z., Hamar, P., Mozes, M. M., Kokeny, G., Rosivall, L., Sebe, A. Characterization and role of SCAI during renal fibrosis and epithelial-to-mesenchymal transition. Am. J. Path. 182: 388-400, 2013. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/4/2021.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

70 kDa

Suppressor of cancer cell invasion

Protein SCAI

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.