Anti-SCARA5 Antilichaam

Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains the collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery.

Boster Bio Anti-SCARA5 Antibody (Catalog # A09571) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Tesr, NET33, Scavenger receptor class A member 5, Scavenger receptor hlg

SCARA5

Q6ZMJ2

Human

At least four isoforms of SCARA5 are known to exist; this antibody will detect all four isoforms.

SCARA5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SCARA5. The immunogen is located within amino acids 350 - 400 of SCARA5.

ELISA, WB, ICC, IF

Homeostasis

SCARA5 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) .

SCARA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A09571

53994 MW

Scavenger receptor class A, member 5 (putative)

Cell membrane

Bovine, Mouse, Chicken, Rat

Scavenger receptor class A, member 5 (putative)

IgG

SCARA5 Antibody is supplied in PBS containing 0.02% sodium azide.