Anti-SEC22B Antibody Picoband® fluoro488 Vervoeging

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene. The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.

ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB

SEC22B

9554

O75396

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SEC22B recombinant protein (Position: M6-A197) .

Brain; neural-specific.

Flow Cytometry

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Immunogen affinity purified.

Liquid

Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

1. Hay, J. C., Chao, D. S., Kuo, C. S., Scheller, R. H. Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell 89: 149-158, 1997. 2. Mao, M., Fu, G., Wu, J.-S., Zhang, Q.-H., Zhou, J., Kan, L.-X., Huang, Q.-H., He, K.-L., Gu, B.-W., Han, Z.-G., Shen, Y., Gu, J., Yu, Y.-P., Xu, S.-H., Wang, Y.-X., Chen, S.-J., Chen, Z. Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. Proc. Nat. Acad. Sci. 95: 8175-8180, 1998. 3. Parlati, F., McNew, J. A., Fukuda, R., Miller, R., Sollner, T. H., Rothman, J. E. Topological restriction of SNARE-dependent membrane fusion. Nature 407: 194-198, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

25 kDa

6

ELAV like RNA binding protein 2

Cytoplasm. Nucleus. Cytoplasm.

AP-2 complex subunit mu

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.