Anti-Secernine-1 SCRN1 Antilichaam

SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

Boster Bio Anti-Secernin-1 SCRN1 Antibody (Catalog # A10002) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

SES1, KIAA0193, Secernin-1

SCRN1

Q12765

Human, Mouse, Rat

SCRN1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SCRN1. The immunogen is located within amino acids 320 - 370 of SCRN1.

ELISA, WB, IHC-P, IF

Cancer, Cell Cycle

SCRN1 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity) . .

SCRN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A10002

46382 MW

Secernin 1

Cytoplasm .

Bovine

Secernin 1

IgG

SCRN1 Antibody is supplied in PBS containing 0.02% sodium azide.