Anti-Septine 2/SEPTIN2 Antibody Picoband® fluoro488 Vervoeging

Septin 2, also known as SEPT2, is a protein which in humans is encoded by the SEPT2 gene. Enables identical protein binding activity. Predicted to be involved in several processes, including cilium assembly; regulation of exocytosis; and smoothened signaling pathway. Predicted to act upstream of or within regulation of L-glutamate import across plasma membrane and regulation of protein localization. Located in several cellular components, including cytoskeleton; photoreceptor connecting cilium; and sperm annulus. Part of septin complex.

NADH-ubiquinone oxidoreductase chain 2; NADH dehydrogenase subunit 2; Mtnd2; mt-Nd2; Nd2

SEPTIN2

4735

Q15019

Human, Monkey, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Septin 2/SEPTIN2 recombinant protein (Position: M1-E326) .

Ubiquitously expressed.

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1. Xu C et al. Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma. Cancer Sci 110:540-549 (2019) . 2. Omrane M et al. Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity. iScience 13:138-153 (2019) . 3. Akil A et al. Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV. Nat Commun 7:12203 (2016) .

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14377 MW

6

NADH dehydrogenase 2, mitochondrial

Mitochondrion inner membrane. Multi-pass membrane protein.

Lymphocyte antigen 6A-2/6E-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.