Anti-SERBP1 Antibody Picoband® 31.0647 Vervoeging

Plasminogen activator inhibitor 1 RNA-binding protein (serbp1) is a protein that in humans is encoded by the SERBP1 gene. Enables SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Involved in PML body organization. Located in cytosol and nucleus.

C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; G-protein coupled receptor 2; CCR10; GPR2

SERBP1

26135

Q8NC51

Human, Mouse, Rat

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence at the C-terminus of human SERBP1, identical to the related mouse and rat sequences.

Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.

1. Gross, M. B. Personal Communication. Baltimore, Md. 5/29/2014. 2. Heaton, J. H., Dlakic, W. M., Dlakic, M., Gelehrter, T. D. Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the type-1 plasminogen activator inhibitor mRNA. J. Biol. Chem. 276: 3341-3347, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

C-C motif chemokine receptor 10

Cell membrane, Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.