Anti-SFR1 Antibody Picoband® 0,00647 Vervoeging

SFR1 is a component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.

Trem-like transcript 1 protein; TLT-1; Triggering receptor expressed on myeloid cells-like protein 1; TREML1; TLT1; UNQ1825/PRO3438

SFR1

119392

Q86XK3

Human, Mouse, Rat

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence in the middle region of human SFR1.

Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Flow Cytometry

Cardiovascular, Immunology, Innate Immunity, Macrophage/Inflammation, Platelets, Protein Phosphorylation, Signal Transduction

Immunogen affinity purified.

Liquid

Cell surface receptor that may play a role in the innate and adaptive immune response. .

1. Akamatsu, Y., Jasin, M. Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet. 6: e1001160, 2010. Note: Electronic Article. 2. Feng, Y., Singleton, D., Guo, C., Gardner, A., Pakala, S., Kumar, R., Jensen, E., Zhang, J., Khan, S. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. PLoS One 8: e68075, 2013. Note: Electronic Article. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 8/17/2015.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

32679 MW

6

Trem-like transcript 1 protein

Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151) . Transported to the cell surface after stimulation by thrombin (PubMed:15100151) . Soluble fragments can be released into the serum by proteolysis (PubMed:16505478) .

Trem-like transcript 1 protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.