Anti-SFTPA1 Antibody Picoband® fluoro488 Vervoeging

Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Pulmonary surfactant-associated protein A1; PSP-A; PSPA; SP-A; SP-A1;35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; Collectin-4; SFTPA1; COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B

SFTPA1

653509

Q8IWL2

Human, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1, different from the rat sequence by two amino acids.

Expressed in neurons of the rolandic area of the brain (at protein level) . Expressed in the brain.

Flow Cytometry

Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Signal Transduction

Immunogen affinity purified.

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Liquid

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

1. Moore, K. J., D'Amore-Bruno, M. A., Korfhagen, T. R., Glasser, S. W., Whitsett, J. A., Jenkins, N. A., Copeland, N. G. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992. 2. Ramet, M., Lofgren, J., Albo, O.-P., Hallman, M. Surfactant protein-A gene locus associated with recurrent otitis media. J. Pediat. 138: 266-268, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

26242 MW

No cross reactivity with other proteins.

6

Pulmonary surfactant-associated protein A1

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Belongs to the SFTPA family.

Pulmonary surfactant-associated protein A1 (PSP-A/PSPA/SP-A/SP-A1)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.