Anti-SFXN3 Antibody Picoband®

SFXN3, a mitochondrial membrane protein, is a member of sideroflexin family. Serum anti-SFXN3 autoantibody was elevated in early stage of the oral squamous cell carcinoma significantly, indicating its clinical value for diagnosis of oral squamous cell carcinoma.

Boster Bio Anti-SFXN3 Antibody Picoband® catalog # A14648-1. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

DAP3-binding cell death enhancer 1; Death ligand signal enhancer; DELE1; DELE; KIAA0141

SFXN3

81855

Q9BWM7

Human

No cross-reactivity with other proteins.

E.coli-derived human SFXN3 recombinant protein (Position: D32-L321) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

ELISA, Flow Cytometry, IF, IHC, WB

Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.

1. Fleming, M. D., Campagna, D. R., Haslett, J. N., Trenor, C. C., III, Andrews, N. C. A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 15: 652-657, 2001. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 12/17/2013. 3. Kory, N., Wyant, G. A., Prakash, G., iut de Bos, J., Bottanelli, F., Pacold, M. E., Chan, S. H., Lewis, C. A., Wang, T., Keys, H. R., Guo, Y. E., Sabatini, D. M. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science 362: eaat9528, 2018. Note: Electronic Article.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A14648-1

64099 MW

36 kDa

6

DAP3 binding cell death enhancer 1

Mitochondrion.

DAP3 binding cell death enhancer 1

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.