Anti-SGCZ Antibody Picoband® 31.0550 Vervoeging

The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.

SGCZ; Zeta-sarcoglycan; Zeta-SG; ZSG1

SGCZ

137868

Q96LD1

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human SGCZ recombinant protein (Position: M1-L245) . Human SGCZ shares 97.1% amino acid (aa) sequence identity with mouse SGCZ.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Wheeler, M. T., Zarnegar, S., McNally, E. M. Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Hum. Molec. Genet. 11: 2147-2154, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

33 kDa

6

Sarcoglycan zeta

Zeta-sarcoglycan

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.