Anti-SH2D3C Antibody Picoband®

SH2 domain containing 3C, also known as SH2D3C, is a protein that in humans is encoded by the SH2D3C gene. This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.

Boster Bio Anti-SH2D3C Antibody Picoband® catalog # A04497-1. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

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SH2D3C

10044

Q8N5H7

Human

No cross reactivity with other proteins.

E.coli-derived human SH2D3C recombinant protein (Position: D48-H789) . Human SH2D3C shares 86.1% amino acid (aa) sequence identity with mouse SH2D3C.

Expressed in all tissues.

WB, Flow Cytometry, ELISA

Signal Transduction, Signaling Pathway, Small G Proteins

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Browne, C. D., Hoefer, M. M., Chintalapati, S. K., Cato, M. H., Wallez, Y., Ostertag, D. V., Pasquale, E. B., Rickert, R. C. SHEP1 partners with CasL to promote marginal zone B-cell maturation. Proc. Nat. Acad. Sci. 107: 18944-18949, 2010. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/4/2012. 3. Lu, Y., Brush, J., Stewart, T. A. NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway. J. Biol. Chem. 274: 10047-10052, 1999.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A04497-1

52588 MW

94 kDa

6

Serine/threonine-protein kinase AtPK1/AtPK6

Cytoplasm. Nucleus.

Serine/threonine-protein kinase AtPK1/AtPK6

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.