Anti-SHC-transformerend eiwit 4 SHC4 Antilichaam

Boster Bio Anti-SHC-transforming protein 4 SHC4 Antibody catalog # A10841. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

SHC-transforming protein 4; Rai-like protein; RaLP; SHC-transforming protein D; hShcD; Src homology 2 domain-containing-transforming protein C4; SH2 domain protein C4; SHC4; SHCD; UNQ6438/PRO21364

SHC4

Q6S5L8

Human, Mouse

Recombinant fusion protein of human SHC4 (NP_976224.3) .

Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential.

WB, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10841

68785 MW

SHC-transforming protein 4

Cell junction, synapse, postsynaptic cell membrane. Colocalized with MUSK at the neuromuscular junction. .

SHC-transforming protein 4

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2