Anti-SHCD/SHC4 Antibody Picoband®

Predicted to enable receptor tyrosine kinase binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within several processes, including apoptotic process; positive regulation of cell population proliferation; and stem cell differentiation. Predicted to be located in postsynaptic membrane. Predicted to be active in plasma membrane.

Boster Bio Anti-SHCD/SHC4 Antibody Picoband® catalog # A10841-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

SHC4

399694

Q6S5L8

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SHCD/SHC4 recombinant protein (Position: Q57-Q519) .

Brain. Expression restricted to astrocytes.

WB, ELISA

Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

1. Ahmed, S. B. M., Prigent, S. A. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell. Signal. 26: 32-40, 2014. 2. Fagiani, E., Giardina, G., Luzi, L., Cesaroni, M., Quarto, M., Capra, M., Germano, G., Bono, M., Capillo, M., Pelicci, P., Lanfrancone, L. RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas. Cancer Res. 67: 3064-3073, 2007. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 02/27/2017.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10841-1

29370 MW

69 kDa

NOVA alternative splicing regulator 2

Nucleus.

Aquaporin-6

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.