Anti-SHP1 PTPN6 Konijn Monoklonale Antilichaam

Boster Bio Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody catalog # M00938. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Tyrosine-protein phosphatase non-receptor type 6;3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1; PTPN6; HCP, PTP1C

PTPN6

5777

P29350

Human, Mouse, Rat

A synthesized peptide derived from human SHP1

Clone: CGH-16

Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.

WB, IHC

Cancer, Cell Biology, Cell Cycle, Developmental Biology, G Protein Signaling, Kinases/Phosphatases, Organogenesis, Signal Transduction, Signaling Pathway

Affinity-chromatography

0.5mg/ml

Liquid

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00938

67561 MW

78 kDa

Tyrosine-protein phosphatase non-receptor type 6

Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity) . Shuttles between the cytoplasm and nucleus via its association with PDPK1. .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.