Anti-SHQ1 Antibody Picoband® 0,00647 Vervoeging

SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

SHQ1

55164

Q6PI26

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human SHQ1 recombinant protein (Position: M1-D277) .

Ubiquitous. Highly expressed in brain. .

Flow Cytometry

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

1. Bizarro, J., Meier, U. T. Inherited SHQ1 mutations impair interaction with NAP57/dyskerin, a major target in dyskeratosis congenita. Molec. Genet. Genomic Med. 5: 805-808, 2017. 2. Grozdanov, P. N., Roy, S., Kuttur, N., Meier, U. T. SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs. RNA 15: 1188-1197, 2009. [PubMed: 19383767, images, related citations] [Full Text] 3. Hartz, P. A. Personal Communication. Baltimore, Md. 12/3/2010.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Protein NDRG3

Membrane ; Single-pass type I membrane protein .

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.