Anti-SIPA1L3 Antilichaam

STEAP3 (Signal-induced proliferation-associated 1-like protein 3) is also named as KIAA0545 and SPAL3. STEAP3 is a member of the STEAP family and is composed of a six-transmembrane domain at the COOH-terminal domain and a cytoplasmic N-terminal oxidoreductase domain, which is essential for iron and copper uptake (PMID:16227996) . STEAP3 contains a functional p53-binding site in its promoter and can be upregulated following p53 activation to enhance cell death in myeloid leukemia cell line and breast cancer cells (PMID: 18617898) . By interacting with Nix, a pro-apoptotic Bcl-2 family member, and Myt1 kinase, a negative regulator of the G2/M transition, STEAP3 overexpression promotes apoptosis and inhibits G2/M transition in cell cycle progression (PMID: 12606722, PMID: 10504341) .

Boster Bio Anti-SIPA1L3 Antibody catalog # A10403-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

SPA-1-like protein 3; SPA 1 like protein 3; SIPA1-like protein 3; SIPA1 like protein 3; Signal-induced proliferation-associated 1-like protein 3

SIPA1L3

O60292

Human, Mouse, Rat

E.coli-derived human SIPA1L3 recombinant protein (Position: T3-D298) .

WB, IHC, ICC, IF, IP, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10403-1

Signal induced proliferation associated 1 like 3

Signal-induced proliferation-associated 1-like protein 3

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.