Anti-SLC40A1 Antibody Picoband®

Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the Ferroportin (Fpn) Family.

Boster Bio Anti-SLC40A1 Antibody Picoband® catalog # A01953-2. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5; IGFBP5; IBP5

SLC40A1

30061

Q9NP59

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SLC40A1 recombinant protein (Position: M1-V571) .

Osteosarcoma, and at lower levels in liver, kidney and brain.

ELISA, Flow Cytometry, IF, IHC, WB

Growth Factors/Hormones, Lipid Signaling, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

1. Agarwal, S., Sankar, V. H., Tewari, D., Pradhan, M. Ferroportin (SLC40A1) gene in thalassemic patients of Indian descent. (Letter) Clin. Genet. 70: 86-87, 2006. 2. Cazzola, M., Cremonesi, L., Papaioannou, M., Soriani, N., Kioumi, A., Charalambidou, A., Paroni, R., Romtsou, K., Levi, S., Ferrari, M., Arosio, P., Christakis, J. Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3) . Brit. J. Haemat. 119: 539-546, 2002. 3. Cremonesi, L., Forni, G. L., Soriani, N., Lamagna, M., Fermo, I., Daraio, F., Galli, A., Pietra, D., Malcovati, L., Ferrari, M., Camaschella, C., Cazzola, M. Genetic and clinical heterogeneity of ferroportin disease. Brit. J. Haemat. 131: 663-670, 2005. Note: Erratum: Brit. J. Haemat. 132: 806 only, 2006.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A01953-2

30570 MW

70 kDa

6

Insulin-like growth factor-binding protein 5

Secreted.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.