Anti-SLC40A1 Antibody Picoband® 310647 Vervoeging

Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the Ferroportin (Fpn) Family.

Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5; IGFBP5; IBP5

SLC40A1

30061

Q9NP59

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SLC40A1 recombinant protein (Position: M1-V571) .

Osteosarcoma, and at lower levels in liver, kidney and brain.

Flow Cytometry

Growth Factors/Hormones, Lipid Signaling, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

1. Agarwal, S., Sankar, V. H., Tewari, D., Pradhan, M. Ferroportin (SLC40A1) gene in thalassemic patients of Indian descent. (Letter) Clin. Genet. 70: 86-87, 2006. 2. Cazzola, M., Cremonesi, L., Papaioannou, M., Soriani, N., Kioumi, A., Charalambidou, A., Paroni, R., Romtsou, K., Levi, S., Ferrari, M., Arosio, P., Christakis, J. Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3) . Brit. J. Haemat. 119: 539-546, 2002. 3. Cremonesi, L., Forni, G. L., Soriani, N., Lamagna, M., Fermo, I., Daraio, F., Galli, A., Pietra, D., Malcovati, L., Ferrari, M., Camaschella, C., Cazzola, M. Genetic and clinical heterogeneity of ferroportin disease. Brit. J. Haemat. 131: 663-670, 2005. Note: Erratum: Brit. J. Haemat. 132: 806 only, 2006.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

30570 MW

6

Insulin-like growth factor-binding protein 5

Secreted.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.