Anti-SLC4A8 Antilichaam

Boster Bio Anti-SLC4A8 Antibody catalog # A08194. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na (+) -driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3; SLC4A8

SLC4A8

Q2Y0W8

Human, Mouse, Rat

Recombinant fusion protein of human SLC4A8 (NP_001035049.1) .

Expressed in the pyramidal cells of the hippocampus (at protein level) . Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex.

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3 (-) exchange with a Na (+) :HCO3 (-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3 (-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3 (-) into the cells. Also mediates lithium-dependent HCO3 (-) cotransport. May be regulated by osmolarity.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08194

122938 MW

WB: 1:500-1:2000

Electroneutral sodium bicarbonate exchanger 1

Membrane

Electroneutral sodium bicarbonate exchanger 1

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2